Cyst vs. Lipoma: Key Differences and How to Tell Them Apart
Published on October 29, 2024
Key Takeaway
While cysts and lipomas are both common benign growths, they have distinct characteristics in terms of composition, appearance, and treatment approaches that can help differentiate between them.
Introduction
Finding an unexplained lump under your skin can be alarming, but more often than not, it's likely to be a benign growth such as a cyst or a lipoma. While these two types of lumps share some similarities, they have distinct characteristics that set them apart. Understanding these differences is crucial for proper diagnosis and treatment. In this article, we'll explore the key distinctions between cysts and lipomas, helping you better understand what might be causing that bump under your skin.
What is a Cyst?
A cyst is a sac-like pocket of tissue that can be filled with fluid, air, or other materials. Cysts can develop almost anywhere in the body and vary greatly in size. According to Healthline, cysts typically have the following characteristics:
- A more defined shape than lipomas
- Firmer to the touch
- Less mobile when pressed
- Can grow larger than 3 centimeters
- May be painful
- Often cause redness and irritation of the surrounding skin
What is a Lipoma?
Lipomas, on the other hand, are benign tumors composed of fat cells. As described in StatPearls, lipomas have these distinguishing features:
- Soft, rubbery consistency
- Usually painless
- Mobile when pressed (often described as having a "slip sign")
- Typically range from 1 to 10 centimeters in size
- Most commonly found on the trunk, shoulders, neck, and arms

Key Differences Between Cysts and Lipomas
While cysts and lipomas can sometimes look similar, there are several key differences that can help distinguish between them:
1. Composition
Cysts are filled with fluid or semi-fluid material, while lipomas are composed of fat cells. This difference in composition affects their texture and appearance.
2. Texture
Cysts tend to be firmer and have a more defined shape, whereas lipomas are softer and have a rubbery feel. Healthline notes that lipomas can be easily moved within the breast tissue, unlike cysts.
3. Mobility
Lipomas are typically more mobile under the skin when pressed, often described as having a "slip sign." Cysts, in contrast, are usually less mobile.
4. Size
While both can vary in size, lipomas generally don't grow larger than 3 centimeters, as mentioned by Healthline. Cysts, however, can sometimes grow larger.
5. Pain and Discomfort
Cysts are more likely to be painful or cause discomfort, especially if they become infected. Lipomas are usually painless unless they press on nearby nerves or contain many blood vessels.
6. Skin Appearance
Cysts often cause redness and irritation of the surrounding skin, particularly if infected. Lipomas typically don't affect the appearance of the overlying skin.

Diagnosis and Treatment
While some characteristics can help differentiate between cysts and lipomas, a definitive diagnosis often requires professional medical evaluation. A study published in American Family Physician suggests that ultrasound is increasingly used to confirm lipoma diagnosis, while deeper lesions may require MRI or CT scans to rule out more serious conditions like liposarcoma.
Treatment approaches also differ:
- Cysts may be treated with drainage, steroid injections, or surgical removal if they cause discomfort or cosmetic concerns.
- Lipomas are often left alone unless they cause pain, affect function, or are cosmetically bothersome. When removal is necessary, surgical excision is the most common approach.
When to Seek Medical Attention
While most cysts and lipomas are benign, it's important to consult a healthcare provider if you notice:
- Rapid growth of the lump
- Pain or tenderness
- Changes in skin color or texture over the lump
- Any lump larger than 5 cm
Conclusion
Understanding the differences between cysts and lipomas can help alleviate concerns and guide you in seeking appropriate medical care. While these growths are usually harmless, proper diagnosis is crucial to rule out more serious conditions. If you're unsure about a lump you've discovered, don't hesitate to consult with a healthcare professional for an accurate diagnosis and personalized treatment plan.