HPV Bumps on Back of Tongue: Causes, Symptoms, and Treatment Options
Published on September 4, 2024
Key Takeaway
While HPV can cause bumps on the back of the tongue, it's relatively uncommon and often benign, but proper diagnosis and treatment are crucial for ruling out more serious conditions.
Introduction
Human Papillomavirus (HPV) is a common viral infection that can affect various parts of the body, including the mouth and throat. While HPV is often associated with genital warts and cervical cancer, it can also cause lesions in the oral cavity, including bumps on the back of the tongue. This article will explore the causes, symptoms, and treatment options for HPV-related bumps on the back of the tongue, as well as when to seek medical attention.
Understanding HPV and Its Relation to Oral Lesions
HPV is a group of viruses that can infect the skin and mucous membranes. There are over 100 types of HPV, but only a few are known to cause oral lesions. According to Healthline, HPV can cause several types of bumps inside the mouth, including on the tongue. One of the more common growths, called squamous cell papilloma, can look a lot like a skin tag on the tongue.

Symptoms and Appearance of HPV Bumps on the Back of Tongue
HPV-related bumps on the back of the tongue may present with the following characteristics:
- Flesh-colored or slightly raised bumps
- Smooth or slightly rough texture
- Painless in most cases
- May appear as a single bump or in clusters
- Can vary in size from a few millimeters to several centimeters
It's important to note that these bumps can sometimes be confused with other oral conditions. Valencia Higuera from Healthline points out that not every bump on the tongue is a wart or HPV-related. Other possibilities include canker sores, cold sores, or even oral thrush.
Prevalence and Risk Factors
The prevalence of HPV-related oral lesions, particularly on the back of the tongue, varies across studies. A study by Xinyu Ren et al. (2020) found that HPV-related lesions are more common in the oropharynx, which includes the base of the tongue, compared to the oral cavity. However, the overall prevalence of HPV in oral tongue cancers is relatively low.
Risk factors for developing HPV-related bumps on the back of the tongue include:
- Unprotected oral sex
- Multiple sexual partners
- Weakened immune system
- Smoking and alcohol consumption (may increase susceptibility)
Diagnosis and Medical Evaluation
If you notice persistent bumps on the back of your tongue, it's essential to seek medical evaluation. A healthcare professional will typically perform the following:
- Visual examination of the oral cavity
- Detailed medical history
- Biopsy of the lesion for histopathological examination
- HPV DNA testing to identify the specific HPV type
Xin-Hua Liang et al. (2008) emphasize the importance of proper diagnosis, as HPV-related lesions can sometimes mimic other conditions, including more serious ones like oral cancer.
Treatment Options for HPV Bumps on the Back of Tongue
Treatment for HPV-related bumps on the back of the tongue depends on various factors, including the size of the lesion, symptoms, and the patient's overall health. Common treatment options include:
- Watchful waiting: Many HPV-related lesions may resolve on their own within two years, as noted by Valencia Higuera in another Healthline article.
- Surgical excision: For larger or symptomatic lesions, surgical removal may be recommended.
- Laser therapy: CO2 laser can be used to remove the lesions with minimal scarring.
- Cryotherapy: Freezing the lesion with liquid nitrogen can be effective for smaller bumps.
- Topical treatments: In some cases, topical medications may be prescribed to help reduce the size of the lesions.

Prevention and Long-term Outlook
Preventing HPV-related bumps on the back of the tongue involves reducing the risk of HPV infection. This includes:
- Practicing safe sex, including using protection during oral sex
- Limiting the number of sexual partners
- Getting vaccinated against HPV (ideally before becoming sexually active)
- Maintaining good oral hygiene
- Avoiding tobacco and excessive alcohol consumption
The long-term outlook for individuals with HPV-related bumps on the back of the tongue is generally good. Nika Cyrus et al. (2015) reported cases where HPV-related oral lesions resolved after HPV vaccination, suggesting potential therapeutic benefits of the vaccine even after infection.
Conclusion
While HPV bumps on the back of the tongue can be concerning, they are often benign and may resolve on their own. However, it's crucial to seek medical evaluation for any persistent oral lesions to rule out more serious conditions. With proper diagnosis and treatment, most cases can be managed effectively. Remember that prevention through safe sexual practices and HPV vaccination remains the best approach to reducing the risk of HPV-related oral lesions.